RNA Details
Disease Name
heart failure
Tissue
heart
RNA Symbol
mir-214
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
PCR; Masson's trichrome staining etc.
Target
NCX1
Pathway
NA
PubMed ID
Title
MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca2+ overload and cell death
Year
2012
Function
"The cardioprotective roles of miR-214 during ir injury were attributed to repression of the mrna encoding sodium/calcium exchanger 1 (ncx1), a key regulator of ca + influx; And to repression of several downstream effectors of ca + signaling that mediate cell death."